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IMCI training video: Exercise G - Practice the exercise of skin pinch
C-peptide A substance the pancreas releases into the bloodstream in equal amounts to insulin. While being stored in pancreatic beta cells , proinsulin includes both insulin and C-peptide, which is freed before insulin secretion into the blood. Currently, since pharmaceutical insulin does not contain C-peptide, a C-peptide level test will show how much insulin the body is making. Insulin is prepared as two insulin molecules linked by a c-peptide. When insulin is secreted, C-peptide is released as well. It has in recent years been shown to have hormone properties, so far chiefly in connection with arterial vessel muscle tone. It has been shown to ameliorate some diabetic complications, such as neuropathy and microvascular damage. C-peptide varies much more between animal species than does insulin itself. Calcium channel blocker Calcium ions are used in many cells, including beta cells, as a signaling mechanism. Since it does not ordinarily pass through cell membranes, protein pores in cell membranes are used to provide a channel through which it can be 'pumped' — an activity which requires energy if done against a concentration gradient. Callus A small area of skin, usually on the foot, that has become thick and hard from rubbing or pressure as a result of increased production of surface skin i. Podiatry defines a callus as a skin lesion, and if it becomes cracked or internally separates, infection can follow, often with no warning signs. Calluses may lead to other problems such as serious infection. Shoes that fit well aid in reducing callus formation as they reduce localized rubbing and friction. Calluses are important risk factors for diabetics, in part because of changes in skin or vasculature characteristic of feet and lower legs in diabetics. Calorie a measure of the chemical energy in a specific amount of material. The food Calorie resulting from combustion with oxygen from the atmosphere is x the calorie used in heat studies i. Not all calories in food are actually usable. For instance, sawdust is largely cellulose i. Calories relevant to diet and so to diabetics come only from those substances in food which can actually be used by the body. Thus, protein is not normally used for fuel, and so should not be counted as a food calorie in normal situations; nevertheless, it is usually taken into account. The amount of usable calories in food is less than the amount measured in a calorimeter, and requires more care to determine. For instance, starch in plant foods is not readily available to be processed in digestion. Capillary a very small blood vessel. At one end of a capillary is a connection to the body's arteries and at the other end of a capillary is a connection to the body's veins. It is in the capillaries that most gas exchange takes place oxygen out of the blood into the tissues, and carbon dioxide into the blood. The reverse exchange happens in the capillaries of the lungs. Capillaries are controlled by very small muscles which, together, affect blood pressure very substantially. Those muscles are in turn controlled by, among other things, the presence or absence of insulin and probably C-peptide in the blood.
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